Effect of commensals and probiotics on visceral sensitivity and pain in irritable bowel syndrome

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Probiotics and irritable bowel syndrome

BACKGROUND Irritable bowel syndrome (IBS) is a major cause of abdominal discomfort and gut dysfunction worldwide. It is a poorly understood functional gastrointestinal disorder for which no effective medication is available. It is a benign condition, but its social and economic burden is significant. The symptoms consist of abdominal pain, bloating, flatulence, and irregular bowel movements. Al...

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Probiotics and irritable bowel syndrome.

Irritable bowel syndrome (IBS) is common gastrointestinal problems. It is characterized by abdominal pain or discomfort, and is associated with changes in stool frequency and/or consistency. The etiopathogenesis of IBS may be multifactorial, as is the pathophysiology, which is attributed to alterations in gastrointestinal motility, visceral hypersensitivity, intestinal microbiota, gut epitheliu...

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Probiotics and Irritable Bowel Syndrome

While a rationale for the use of probiotics can be developed for a number of gastrointestinal symptoms and syndromes and an experimental basis for their use continues to emerge, irritable bowel syndrome (IBS) has become the focus of much interest in this regard. IBS has also attracted attention because of recent revelations with regard to the potential roles of the enteric flora and immune acti...

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Probiotics in Irritable Bowel Syndrome

biotics seemed to be promising. Probiotics are living organisms which, when ingested in certain numbers, exert health benefits beyond inherent basic nutrition [7] . It is well known that specific bacteria strains have numerous positive effects in the gastrointestinal tract. Probiotics reduce the adherence of pathogen bacteria on the epithelial cells and thus the ability of pathogen bacterial tr...

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Probiotics in Irritable Bowel Syndrome

biotics seemed to be promising. Probiotics are living organisms which, when ingested in certain numbers, exert health benefits beyond inherent basic nutrition [7] . It is well known that specific bacteria strains have numerous positive effects in the gastrointestinal tract. Probiotics reduce the adherence of pathogen bacteria on the epithelial cells and thus the ability of pathogen bacterial tr...

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ژورنال

عنوان ژورنال: Gut Microbes

سال: 2014

ISSN: 1949-0976,1949-0984

DOI: 10.4161/gmic.29796